Page 71 - CIBEROBN-2015-eng

Most relevant scientific articles
Research Groups
KONIECZNA J., SáNCHEZ J., PALOU M., PICó C., PALOU A.. Blood cell transcriptomic-based early biomarkers of ad- verse programming effects of gestational calorie res- triction and their reversibility by leptin supplementation. Scientific Reports. 2015;5.
PRIEGO T., SáNCHEZ J., PICó C., AHRENS W., DE HENAUW S., KOURIDES Y. ET AL. TAS1R3 and UCN2 transcript levels in blood cells are associated with sugary and fatty food con- sumption in children. Journal of Clínical Endocrinology and Metabolism. 2015;100(9):3556-3564.
KONIECZNA J., PALOU M., SáNCHEZ J., PICó C., PALOU A.. Leptin intake in suckling rats restores altered T3 levels and markers of adipose tissue sympathetic drive and function
Highlights
During the year 2015, the group headed by Prof. Andreu Palou has participated in three European projects (BIOCLAIMS, I.FAMILY and DIABAT), in one project of the National Plan (EPIMILK, AGL2012- 33692) and in 6 projects of private entities: a project of the Fundación Ramón Areces, other of Biosearch, and three of Alimentómica S.L., as well as in two re- search networks (MARCASALUD and IBERCAROT). It is worth noting the European project BIOCLAIMS (“BIOmarkers of Robustness of Metabolic Homeos- tasis for Nutrigenomics-derived Health CLAIMS Made on Food”, FP7-244995, contract n. 244885), headed by Palou. As a remarkable result obtained in this project, the group has identified a nutrigeno- mic biomarker, in blood, able to predict since early ages predisposition to develop obesity (these re- sults have been patented, PCT/ES2015/070216). In relation to the search of biomarkers of obesity and nutrition, the group has also participated in the pro- ject I.FAMILY (“Determinants of eating behaviour in
caused by gestational calorie restriction. International Journal of Obesity. 2015;39(6):959-966.
GARCíA-RUIZ E., REYNéS B., DíAZ-RUA R., CERESI E., OLIVER P., PALOU A.. The intake of high-fat diets induces the ac- quisition of brown adipocyte gene expression features in white adipose tissue. International Journal of Obesity. 2015;39(11):1619-1629.
CASTRO H., POMAR C.A., PICó C., SáNCHEZ J., PALOU A.. Ca- feteria diet overfeeding in young male rats impairs the adaptive response to fed/fasted conditions and increases adiposity independent of body weight. International Jour- nal of Obesity. 2015;39(3):430-437.
European children, adolescents and their parents”, Ref. 266044); among the most outstanding results obtained in 2015, blood biomarkers related to su- gary and fatty food consumption in children have been described. Besides, as a result of the participa- tion in the European project DIABAT (“Recruitment and activation of brown adipocytes as preventive and curative theraphy for type 2 diabetes”, HEAL- TH-F2-2011-278373), the group has contributed to go in depth in the understanding of the effect of diet and food compounds on brown adipose tissue activation and in the remodeling of white to brown adipose tissue, which is of therapeutic interest to increase energy expenditure and combat obesity. Furthermore, the group has described the utility of gene expression analysis in blood cells as a tool to perform thermogenic studies with minimum invasi- veness.
Institution: Universitat de les Illes Balears · Contact: Facultad de Ciencias de Mallorca.
Cra. de Valldemossa, km 7.5. 07122 Palma · E.mail: [email protected] · Website: http://palou.uib.es
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