Page 20 - CIBEROBN2016-ENG

P1. Nutrition
Coordinators: Jordi Salas Salvadó and Dolores Corella Piquer The major highlights in this programme in 2016 were as follows:
PREDIMED
• The publication of the PREDIMED study in NEJM 2013 was the one most cited for over 2 years and is at present in third place (Altmetric www.altmetric.com/details/1261724#score)
• The Mediterranean Diet (DMed) is recognised as an effective diet standard for:
Primary prevention of cardiovascular disease in American Diet Guides.
The primary prevention of cerebrovascular accidents in American Guides on primary prevention of strokes. (Stroke 2014;45:3754-832).
The prevention of type 2 diabetes mellitus in Australian Guides on diabetes.
• The results are published in relation to the effects of DMed on weight and waist size: The DMed is slightly superior to the low fat diet in terms of adiposity (Lancet Diabetes Endocrinol 2016;4:666-76).
• A study reveals the importance of omega-3 fatty acids (fish) to prevent retinopathy complications in diabetic patients (JAMA Ophthalmol 2016;134:1142-9).
• PREDIMED is taking part in a genetic meta-analysis including over 197,000 individuals in weight and high blood pressure.
• The first results on metabolites predicting cardiovascular disease are published as a result of a NIH project in Navarre in cooperation with Harvard.
• A meta-analysis on FTO genotype and weight loss is published, including eight clinical trials, in the British Medical Journal.
• A European ERA-NET HDHL project was obtained (López-Miranda and Martínez-González) “Metabolism of fatty acids-bridge between diet and cardiometabolic health”.
• Organisation of the 1st World Conference on the Mediterranean Diet. 6-8 e 2016, Milan, Italy (IP: Serra- Majem).
• Different international projects are requested from the NHI, H2020.
PREDIMED Plus:
• Over 6900 participants randomised.
• >3000 participants have been followed up for over 1 year.
• The first PREDIMED-PLUS work is published.
• A H2020 project is obtained with cognitive function in a subgroup of PREDIMED-PLUS participants.
• PREDIMED PLUS is accepted by the NIH of the United States to join the NHI Consortium for GWAs in clinical trials for weight loss.
SUN project (Universidad de Navarra):
• Article accepted by World Psychiatry (IF>20).
• 22600 participants with 16-year follow-up in the SUN cohort.
Estudio WAHA (Hospital Clínico de Barcelona):
• After completing the WAHA (WAlnuts and Healthy Aging) study, recruiting 700 elderly but cognitively healthy volunteers at the Hospital Clínic de Barcelona and Loma Linda University to compare a diet of walnuts as compared with a control, on cognitive impairment and macular degeneration.
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