Page 25 - CIBEROBN2016-ENG

P5. New strategies and Biomarkers
Coordinator: Andreu Palou Oliver
In 2016 progress was made in identifying obesity biomarkers and eating behaviour in children as part of the European project I. FAMILY. In rodents, early blood markers of nutritional alterations, risk of obesity
and associated medical complications were also identified. In this period one patent was accepted and published (P201430428) which defines the nutrigenomic biomarker in the blood able to predict the predisposition to develop obesity in early stages and the international patent was extended to Russia. We should also stress the identification of markers connecting hepatic steatosis associated with the intake of unbalanced diets with a greater risk of lesions in the liver, including liver cancer. Progress has also been made in the identification of the importance of epigenetic regulation, of microRNA and of the genotype
in obesity and weight loss in humans. Guides have been written on personalised nutrition and studies are being carried out on humans intended to develop nutrigenetic-based tests to facilitate control of body weight and weight loss. Of interest in the field of functional nutrition, new methods of identification of bioactive compounds of food (antioxidant compounds) in the blood and urine have been published, of use for analysing their positive effects on health. Some interesting properties from the standpoint of obesity control of bioactive compounds of food, such as glycosaminoglycans, have also been identified. Apart from this, studies which display the positive effects of breast-feeding in children with low weight when born have been carried out. Also with children, as part of the ETIOBE project, based on the implementation
of e-therapy for dealing with child obesity, an innovative mathematical method (“self-organizing map”)
has been used for analysing data of self-registers of eating habits. Protocols have also been established
for measuring physical activity habits in obese children and adolescents, which enable obtaining profiles used for designing personalised physical exercise. In this respect the physical activity programme (PAIDO programme) has been implemented, with the addition of the Marchando con mi Pediatra (Walking with my Doctor), enabling patients and families to go on fast walks in leisure areas supervised by paediatric doctors. The platform has also been prepared for its implementation in the adult population.
In July 2016 the VII Seminario sobre Alimentación y Estilos de Vida Saludables was arranged: “The declarations of healthy properties one decade later and New Food in the European Union” in Palma de Mallorca. The seminar was a joint activity of the excellence network MARCASALUD (MINECO) and of the Programme for New Strategies and Biomarkers (CIBER), and different groups associated with the programme took an active part in the event as speakers.
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Scientific Programmes 25