Page 57 - CIBEROBN2016-ENG

• Molecular and cellular mechanisms related with risk and protective factors for cardiovascular and neurodegenerative disease. Role of high density lipoproteins (HDLs) and low density (LDL), the interaction between diet and intestinal flora, and nutrigenomics.
• Nutritional Epidemiology and Epidemiology and Obesity and Diabetes management.
Most relevant scientific articles
• Hernáez A., Farras M., Fito M. Olive oil phenolic compounds and high-density lipoprotein function. Current Opinion in Lipidology. 2016;27(1):47-53.
• Martín-Peláez S., Castaner O., Sola R., Motilva M.J., Castell M., Pérez-Cano F.J. et al. Influence of phenol-enriched olive oils on human intestinal immune function. Nutrients. 2016;8(4).
• De la Torre R., de Sola S., Hernández G., Farré M., Pujol J., Rodríguez J. et al. Safety and efficacy of cognitive training plus epigallocatechin-3-gallate in young adults with Down’s syndrome (TESDAD): A double-blind, randomised, placebo-controlled, phase 2 trial. The Lancet Neurology. 2016;15(8):801-810.
• Goday A., Calvo E., Vázquez L.A., Caveda E., Margallo T., Catalina-Romero C. et al. Prevalence and clinical characteristics of metabolically healthy obese individuals and other obese/non-obese metabolic phenotypes in a working population: Results from the Icaria study. BMC Public Health. 2016;16(1).
• Fito M., Konstantinidou V. Nutritional genomics and the mediterranean Diet’s effects on human cardiovascular health. Nutrients. 2016;8(4).
Hightlights
The incorporation of two pre-doctoral students (contract i-PFIS and AGAUR) have been achieved the present year.
With regard projects, mention should be made of the granting of a European project linked to the PREDIMED-plus study on impulsivity and cognitive performance (coordination: Dr. Fernández de Aranda, co-coordinator Dr. Salas-Salvador) in the framework of CIBEROBN. In this regard, one of the researchers belongs to CARIN group.
On the other hand, in the context of the PREDIMED-plus Study, two sub-projects are being led on:
• Functionality of HDL: highlight the recent publication in Circulation journal on the benefits of a Mediterranean diet pattern, particularly when it is rich in olive oil, on the functionality of HDL.
• “Halo” effect (coordinators Dr. Goday and Dra. Castañer) on the relatives of participants in clinical trials on lifestyle. The expected results would be that a lifestyle intervention, basically diet and physical activity practice, can also affect the lifestyle of the relatives of the participants to the trial. This project is currently being developed in different scenarios: a / the 10-year follow-up of the PREDIMED Study in the centers of Barcelona (Hospital-Clinic and IMIM); B / in 6 centers of the PREDIMEDplus Study (IMIM, URV, Bellvitge Hospitals and Clinic of Barcelona, and the Epidemiology and Nutrition Centers of the University of Navarra); And c / within the family of patients who will undergo bariatric surgery.
Finally, the project on the effect of green tea components on the cognitive performance of children and adolescents with Down syndrome led by Dr. de la Torre, whose results in the Lancet Neurology had a great impact on the scientific community and media.
OBN
Research groups 57