Grupo de Investigación

Herrero Rodríguez, Laura - CB06/03/0001

» Institución
Universidad de Barcelona

» Centro
Facultad de Farmacia y Ciencias de la Alimentación. Instituto de Biomedicina de la Universidad de Barcelona

» Contacto
Av. Joan XXIII, 27-31
08028 - Barcelona | BARCELONA
Tel. 9024522

Apellido, Nombre	Modalidad	Detalle
Ariza Piquer, Javier	Adscrito	VER FICHA
Balibrea del Castillo, José María	Colaborador	VER FICHA
Casals Farre, Nuria	Adscrito	VER FICHA
Castell escuer, Margarida	Colaborador	VER FICHA
Escoté Miro, Xavier	Adscrito	VER FICHA
Esteve Rafols, Monserrat	Adscrito	VER FICHA
Fadó Andrés, Rut	Adscrito	VER FICHA
Fernández López, José Antonio	Adscrito	VER FICHA
García Gómez, Jorge	Adscrito	VER FICHA
García Roves González, Pablo Miguel	Colaborador	VER FICHA

Our aim is to find new approaches to combat obesity through the following research lines:

1. Enhancing adipose tissue thermogenesis (CPT1A expression, lncRNAs). Herrero’s team.

2. Central activation of brown adipose tissue and satiety (neuronal CPT1A and CPT1C’s role, 3D structure and new inhibitors). Casals and García’s team.

3. Regulation of energy balance and diet (glucocorticoids’ role). Fernández’s team.

4. Adipose tissue in adults and children with obesity (childhood obesity and new biomarkers of obesity). Herrero’s team.

5. Metabolism and mitochondrial function in physiology and disease. García-Rovés’ team.

6. Immune system, inflammation, and microbiota (maternal diet, microbial modulators, exercise, and inflammatory disease). Castell’s team.

7. Effect of nutrients on cognition. Casals’ team.

8. Targeting brain cells to regulate obesity and diabetes. Casals’ team.

9. Dietary impact on the metabolome, transcriptome, and microbiota in cardiometabolic diseases and cognitive decline. Escoté’s team.

Las 10 primeras publicaciones según Factor de impacto (F.I.) de los últimos 4 años:

Helsley R.N., Park S.-H., Vekaria H.J., Sullivan P.G., Conroy L.R., Sun R.C. et al. Ketohexokinase-C regulates global protein acetylation to decrease carnitine palmitoyltransferase 1a-mediated fatty acid oxidation. Journal of Hepatology. 2023;.
PUBMED DOI
da Silva Lima N., Fondevila M.F., Novoa E., Buque X., Mercado-Gomez M., Gallet S. et al. Inhibition of ATG3 ameliorates liver steatosis by increasing mitochondrial function. Journal of Hepatology. 2022;.
PUBMED DOI
Fondevila MF, Fernandez U, Heras V, Parracho T, Gonzalez-Rellan MJ, Novoa E et al. Inhibition of carnitine palmitoyl-transferase 1A in hepatic stellate cells protects against fibrosis.Journal of hepatology. 2022;.
PUBMED DOI
Olazagoitia-Garmendia A., Rojas-Marquez H., Del Mar Romero M., Ruiz P., Agirre-Lizaso A., Chen Y. et al. Inhibition of YTHDF1 by salvianolic acid overcomes gluten-induced intestinal inflammation. Gut. 2023;.
PUBMED DOI
Monelli E., Villacampa P., Zabala-Letona A., Martinez-Romero A., Llena J., Beiroa D. et al. Angiocrine polyamine production regulates adiposity. Nature Metabolism. 2022;4(3):327-343.
PUBMED DOI
Valdecantos M.P., Ruiz L., Folgueira C., Rada P., Gomez-Santos B., Solas M. et al. The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk. Nature Communications. 2024;15(1).
PUBMED DOI
Barahona I., Rada P., Calero-Perez S., Grillo-Risco R., Pereira L., Soler-Vazquez M.C. et al. Ptpn1 deletion protects oval cells against lipoapoptosis by favoring lipid droplet formation and dynamics. Cell Death and Differentiation. 2022;29(12):2362-2380.
PUBMED DOI
Gonzalez-Franquesa A., Gama-Perez P., Kulis M., Szczepanowska K., Dahdah N., Moreno-Gomez S. et al. Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue. Redox Biology. 2022;54.
PUBMED DOI
Mayayo-Vallverdu C., Lopez de Heredia M., Prat E., Gonzalez L., Espino Guarch M., Vilches C. et al. The antioxidant L-Ergothioneine prevents cystine lithiasis in the Slc7a9−/− mouse model of cystinuria. Redox Biology. 2023;64.
PUBMED DOI
Peyman M., Babin-Ebell A., Rodriguez-Rodriguez R., Rigon M., Aguilar-Recarte D., Villarroya J. et al. SIRT1 regulates hepatic vldlr levels. Cell Communication and Signaling. 2024;22(1).
PUBMED DOI

The specific composition of our team is as follows:

The Regulation of lipid metabolism in obesity and diabetes (METALIP) group (www.ub.edu/betaoxi/; Twitter: @betaoxi) located at the Dpt. Biochemistry and Physiology, School of Pharmacy and Food Sciences, Institute of Biomedicine of the University of Barcelona (IBUB), UB is led by Laura Herrero (Associate Professor) and recognized as a Group of Excellence by the Generalitat de Catalunya. The group is composed of 15 researchers: 1 PI, 3 postdocs, 8 PhD students, 1 master student, 1 Erasmus student and 1 research technician.

The Nitrogen-Obesity group located at the Dpt. Biochemistry and Molecular Biomedicine, School of Biology, UB is led by Jose Antonio Fernández (Full professor) and is composed of 4 researchers: 2 full professors and 2 associate professors.

The NeuroLipid group (www.uic.es/neurolipid-group; Instagram: neurolipid_groupuic), located at the School of Medicine and Health Sciences, UIC is led by Núria Casals (Full Professor) and Rosalía Rodriguez (Associate Professor). The group is composed of 12 researchers: 2 PIs, 3 postdocs and 7 PhD students.

The Synthetic Methodology Applied to Bioactive Compounds group (SMBioCom; www.qo.ub.edu/grups/SMBioCom/) located at the Dpt. of Inorganic and Organic Chemistry at the School of Chemistry, UB is led by Jordi García and Xavier Ariza (Full professors). The group is composed of 8 researchers: 2 PIs, 1 postdoc and 5 PhD students.

Xavier Escoté's research group is affiliated with the Dpt. of Biochemistry and Biotechnology and is based at the school of Medicine in Reus, University Rovira i Virgili.

The Autoimmunity and Tolerance group located at the Dpt. Biochemistry and Physiology, School of Pharmacy and Food Sciences, Research Institute of Nutrition and Food Safety, UB is led by Margarida Castell (Full Professor). The group includes 15 researchers: 3 PIs, 4 postdocs, 4 PhD students and 4 master and degree students.

The Metabolism and mitochondrial function in physiology and disease group (https://mmfpd-ub.wixsite.com/mmfpd) located at the Dpt. Physiological sciences, School of Medicine, UB is led by Pablo García-Rovés (Associate Professor), José C Perales (Full Professor) and Andrés Méndez-Lucas (Assistant Professor). The group is composed of 9 researchers: 3 PIs, 1 postdoc and 5 PhD students.